Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.57 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14357798 | 0.96 | CYP3A4 (0.62) | GPBAR1CYP3A4NR1H4PDE3ALMNA | |
| SCHEMBL14357810 | 0.94 | GPBAR1 (0.61) | GPBAR1CYP3A4NR1H4PDE3ALMNA | |
| SCHEMBL14357814 | 0.93 | NR1H4 (0.55) | GPBAR1CYP3A4NR1H4PDE3ALMNA | |
| SCHEMBL14388517 | 0.92 | GPBAR1 (0.67) | GPBAR1CYP3A4NR1H4PDE3ALMNA | |
| SCHEMBL14357812 | 0.90 | GPBAR1 (0.66) | GPBAR1CYP3A4NR1H4PDE3AKMT2A | |
| SCHEMBL14357817 | 0.90 | CYP3A4 (0.53) | GPBAR1CYP3A4NR1H4PDE3ALMNA | |
| SCHEMBL14357780 | 0.89 | GPBAR1 (0.63) | GPBAR1NR1H4PDE3ALMNAKMT2A | |
| SCHEMBL14388512 | 0.88 | CYP3A4 (0.72) | GPBAR1CYP3A4NR1H4PDE3ALMNA | |
| SCHEMBL14468568 | 0.88 | GPBAR1 (0.57) | GPBAR1CYP3A4NR1H4PDE3ALMNA | |
| SCHEMBL14357801 | 0.87 | GPBAR1 (0.65) | GPBAR1CYP3A4NR1H4PDE3ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254247-A1 | Radiation-sensitive resin composition | YAMAMOTO MASAFUMI | 2007-11-01 | — | — | US | disclosed |