Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14358227 | 0.88 | KCNH2 (0.55) | KCNH2 | |
| SCHEMBL14358523 | 0.87 | KCNH2 (0.55) | KCNH2 | |
| SCHEMBL14361397 | 0.82 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL14358775 | 0.82 | KCNH2 (0.71) | KCNH2 | |
| SCHEMBL14358285 | 0.82 | KCNH2 (0.71) | KCNH2 | |
| SCHEMBL14358762 | 0.81 | KCNH2 (0.69) | KCNH2 | |
| Hydrochloric Acid SCHEMBL14358102 | 0.81 | KCNH2 (0.71) | KCNH2 | |
| SCHEMBL14358491 | 0.77 | KCNH2 (0.69) | KCNH2 | |
| SCHEMBL14358359 | 0.77 | KCNH2 (0.52) | KCNH2 | |
| Hydrochloric Acid SCHEMBL14358298 | 0.76 | KCNH2 (0.53) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723737-A1 | BRIDGED BICYCLIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | Kyorin Pharmaceutical Co., Ltd. (JP) | 2014-04-30 | — | — | EP | disclosed |
| WO-2013003383-A1 | BRIDGED BICYCLIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2013-01-03 | — | — | WO | disclosed |