Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 7/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GLB1 | P16278 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259151 | 0.85 | — | — | |
| SCHEMBL14949083 | 0.82 | TDP1 (0.39) | TDP1GBA1SIPYGLGBA2 | |
| SCHEMBL14211655 | 0.77 | — | — | |
| SCHEMBL22914943 | 0.77 | — | — | |
| SCHEMBL18332300 | 0.76 | — | — | |
| SCHEMBL21783304 | 0.75 | GBA1 (0.44) | TDP1GBA1SIPYGLGBA2 | |
| SCHEMBL7100318 | 0.75 | GBA1 (0.44) | TDP1GBA1SIPYGLGBA2 | |
| SCHEMBL924500 | 0.73 | — | — | |
| SCHEMBL1802277 | 0.73 | — | — | |
| SCHEMBL4141863 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2726468-A1 | SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF | Alectos Therapeutics Inc. (CA) | 2014-05-07 | — | — | EP | disclosed |
| WO-2013000085-A1 | SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2013-01-03 | — | — | WO | disclosed |