SCHEMBL143632

SCHEMBL143632

O=C(O)Oc1ccccc1OC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.46
HSD17B10 Q99714 6/20 0.46
ALDH1A1 P00352 6/20 0.46
HPGD P15428 5/20 0.46
MAPT P10636 2/20 0.46
TSHR P16473 2/20 0.46
NAPRT Q6XQN6 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KMT2A Q03164 1/20 0.46
ESR1 P03372 1/20 0.46
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
HMGB1 P09429 1/20 0.46
GGT1 P19440 1/20 0.46
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46
BLM P54132 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
SERPINE1 P05121 1/20 0.45
PTGDR2 Q9Y5Y4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16319433 0.92 HTT (0.48) KDM4EHSD17B10ALDH1A1HPGDMAPT
Methane SCHEMBL8861352 0.90 HSD17B10 (0.41) KDM4EHSD17B10ALDH1A1HPGDMAPT
SCHEMBL21540 0.88 CA1 (0.59) ALDH1A1MAPTTSHRSMN1; SMN2KMT2A
Butane SCHEMBL1395551 0.88 KDM4E (0.47) KDM4EHSD17B10ALDH1A1HPGDTSHR
Ethane SCHEMBL8663454 0.88 KDM4E (0.44) KDM4EHSD17B10ALDH1A1HPGDMAPT
SCHEMBL7017642 0.87 FABP3 (0.44) KDM4EHSD17B10ALDH1A1HPGDMAPT
SCHEMBL571709 0.86 CTNNB1 (0.55) ALDH1A1HPGDTSHRSMN1; SMN2KMT2A
SCHEMBL154582 0.85 GAA (0.52) KDM4EHSD17B10ALDH1A1HPGDMAPT
Propane SCHEMBL7904305 0.84 GLA (0.44) KDM4EHSD17B10ALDH1A1HPGDMAPT
SCHEMBL5708296 0.84 SMN1; SMN2 (0.44) KDM4EHSD17B10ALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2739169-B1 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS MASSACHUSETTS INST TECHNOLOGY (US) 2019-06-12 EP claimed
EP-3271500-B1 ACTIVATION METHOD FOR SILICON SUBSTRATES ATOTECH DEUTSCHLAND GMBH (DE) 2018-06-20 EP claimed
EP-2765150-B1 Resin composition for manufacturing thermoplastic polyester resin by using green catalyst LOTTE CHEMICAL CORP (KR) 2017-11-15 EP claimed
EP-2477958-B1 HIGH SHEAR SYSTEM AND METHOD FOR THE PRODUCTION OF ACIDS H R D CORP (US) 2017-04-12 EP claimed
EP-2237825-B1 IMPROVEMENTS IN OR RELATING TO INHALERS INNOVATA BIOMED LTD (GB) 2016-08-03 EP claimed
CN-103992467-A Resin composition for preparation of thermoplastic polyester resin and polyester resin prepared therefrom LOTTE CHEMICAL CORP 2014-08-20 CN claimed
EP-2765150-A1 Resin composition for manufacturing thermoplastic polyester resin by using green catalyst Lotte Chemical Corporation (KR) 2014-08-13 EP claimed
US-8653224-B1 Resin composition for manufacturing thermoplastic polyester resin by using green catalyst LOTTE CHEMICAL CORPORATION (KR) 2014-02-18 US claimed
US-8153307-B1 Battery including electrolyte with mixed solvent QUALLION LLC (US) 2012-04-10 US claimed
US-7771496-B1 Reduction of impurities in battery electrolyte QUALLION LLC (US) 2010-08-10 US claimed
US-7323537-B2 Catalyst for production of polyester, process for producing polyester using it and titanium-containing polyethylene terephthalate MITSUBISHI CHEMICAL CORPORATION (JP) 2008-01-29 US claimed
EP-1301564-B1 PERSONAL CARE COMPOSITION COMPRISING A PLASTICIZED WATERBORNE POLYURETHANE DISPERSION NOVEON IP HOLDINGS CORP (US) 2006-05-10 EP claimed
EP-1047483-B1 SEPARATION PROCESS ISIS INNOVATION (GB) 2005-12-28 EP claimed
EP-0790974-B1 SUBSTITUTED 4-BIARYLBUTYRIC OR 5-BIARYLPENTANOIC ACIDS AND DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITIORS BAYER AG (US) 2002-08-14 EP claimed
EP-0422108-B1 COMPOSITE ARTICLE RESISTANT TO MOISTURE-INDUCED DEBONDING FULLER H B LICENSING FINANC (US) 1994-08-03 EP claimed
EP-0309400-B1 N-acyloxy hindered amine stabilizers CIBA GEIGY AG (CH) 1994-03-02 EP claimed
EP-0358113-B1 Fountain solution for offset printing HOECHST AG (DE) 1994-02-09 EP claimed
EP-0358113-A2 Fountain solution for offset printing HOECHST AKTIENGESELLSCHAFT (DE) 1990-03-14 EP claimed
US-4340690-A Cyclic organo carbonate and sulfite coupling agents for living polymers of conjugated dienes THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-07-20 US claimed
US-4301258-A OF BROADENED MOLECULAR WEIGHT DISTRIBUTION; HIGH IMPACT PLASTICS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-11-17 US claimed