Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.66 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666997 | 1.00 | DPP4 (0.66) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL666582 | 0.90 | DPP4 (0.77) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL666508 | 0.90 | DPP4 (0.73) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL665379 | 0.90 | DPP4 (0.67) | DPP4DPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL1435740 | 0.90 | DPP4 (0.76) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL4594211 | 0.89 | DPP4 (0.57) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL663330 | 0.89 | DPP4 (0.57) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL667346 | 0.84 | DPP4 (0.65) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL666249 | 0.80 | DPP4 (0.86) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL5660145 | 0.80 | DPP4 (0.86) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441719-B1 | N-SUBSTITUTED PYRROLIDIN DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-03-30 | — | — | EP | disclosed |