Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14360667 | 0.88 | CA1 (0.43) | TAAR1CA1CA2PDE3ACYP1A2 | |
| SCHEMBL10053153 | 0.86 | CA1 (0.47) | CA1CA2PDE3ATMEM97SIGMAR1 | |
| SCHEMBL10053163 | 0.84 | CA1 (0.44) | CA1CA2PDE3ATMEM97SIGMAR1 | |
| SCHEMBL14342327 | 0.83 | CA1 (0.47) | TAAR1CA1CA2PDE3ATMEM97 | |
| SCHEMBL10053161 | 0.83 | CA1 (0.49) | CA1CA2PDE3ATMEM97SIGMAR1 | |
| SCHEMBL10053166 | 0.82 | TAAR1 (0.49) | TAAR1CA1CA2PDE3ASIGMAR1 | |
| SCHEMBL10053182 | 0.82 | CA1 (0.61) | CA1CA2PDE3APDE4APDE4B | |
| SCHEMBL500198 | 0.81 | CA1 (0.59) | CA1CA2PDE3APDE4APDE4B | |
| SCHEMBL12589681 | 0.80 | CA1 (0.49) | TAAR1CA1CA2PDE3APDE4A | |
| SCHEMBL12589684 | 0.80 | CA1 (0.53) | CA1CA2PDE3APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146965-A2 | COMPOUNDS FOR THE TREATMENT OF PERIODONTAL DISEASE | ANACOR PHARMACEUTICALS, INC. (US) | 2007-12-21 | — | — | WO | disclosed |