Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 15/20 | 0.62 |
| ▸ | CDK9 | P50750 | 9/20 | 0.62 |
| ▸ | CDK1 | P06493 | 8/20 | 0.62 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.62 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.55 |
| ▸ | CDK7 | P50613 | 8/20 | 0.55 |
| ▸ | CCNH | P51946 | 5/20 | 0.55 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.55 |
| ▸ | GSK3B | P49841 | 4/20 | 0.55 |
| ▸ | CDK4 | P11802 | 3/20 | 0.55 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.55 |
| ▸ | GSK3A | P49840 | 2/20 | 0.55 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.55 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.55 |
| ▸ | CDK8 | P49336 | 2/20 | 0.55 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.55 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14346539 | 0.92 | CDK2 (0.51) | CDK2CDK9CDK1CDK5CCNE1 | |
| SCHEMBL14364544 | 0.91 | CDK2 (0.59) | CDK2CDK9CDK1CDK5CCNE1 | |
| SCHEMBL14364545 | 0.91 | CDK2 (0.59) | CDK2CDK9CDK1CDK5CCNE1 | |
| SCHEMBL14364537 | 0.91 | CDK2 (0.50) | CDK2CDK9CDK1CDK5CCNE1 | |
| SCHEMBL14364547 | 0.90 | CDK2 (0.58) | CDK2CDK9CDK1CDK5CCNE1 | |
| SCHEMBL14364550 | 0.90 | CDK2 (0.58) | CDK2CDK9CDK1CDK5CCNE1 | |
| SCHEMBL12953698 | 0.88 | CDK2 (0.69) | CDK2CDK9CDK1CDK5CCNE1 | |
| SCHEMBL14346391 | 0.84 | CDK2 (0.44) | CDK2CDK9CDK1CDK5CCNE1 | |
| SCHEMBL14346178 | 0.84 | CDK2 (0.44) | CDK2CDK9CDK1CDK5CCNE1 | |
| SCHEMBL14364538 | 0.83 | CDK2 (0.49) | CDK2CDK9CDK1CDK5CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275963-A1 | PYRAZOLO[1,5-a]PYRIMIDINES | SCHERING CORPORATION | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275963-A1 | PYRAZOLO[1,5-a]PYRIMIDINES | CDK2, CDKN1A, CDK1 | CDK2 1/4885CDK9 8/4885CDK1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.