Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14366123 | 0.88 | F10 (0.54) | F10MEN1KMT2ADEGS1DUSP3 | |
| SCHEMBL6711168 | 0.88 | F10 (0.68) | F10MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL14448418 | 0.87 | F10 (0.53) | F10MEN1KMT2ADEGS1DUSP3 | |
| SCHEMBL14366617 | 0.86 | F10 (0.60) | F10 | |
| SCHEMBL14366428 | 0.79 | F10 (0.56) | F10MEN1KMT2ADEGS1RAB9A | |
| SCHEMBL6712654 | 0.76 | F10 (0.72) | F10RAB9ANPC1TP53SMN1; SMN2 | |
| SCHEMBL14345370 | 0.75 | F10 (0.62) | F10MEN1KMT2A | |
| SCHEMBL14345374 | 0.74 | F10 (0.54) | F10MEN1KMT2A | |
| SCHEMBL14366616 | 0.74 | F10 (0.61) | F10RAB9ANPC1TP53SMN1; SMN2 | |
| SCHEMBL14345382 | 0.74 | F10 (0.54) | F10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |