Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.80 |
| ▸ | PPARG | P37231 | 10/20 | 0.80 |
| ▸ | PPARD | Q03181 | 8/20 | 0.80 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391721 | 1.00 | PPARA (0.80) | PPARAPPARGPPARDLMNAL3MBTL1 | |
| SCHEMBL5379645 | 0.92 | PPARG (0.72) | PPARAPPARGPPARD | |
| SCHEMBL5384053 | 0.90 | PPARG (0.81) | PPARAPPARGPPARD | |
| SCHEMBL14366451 | 0.90 | PPARG (0.81) | PPARAPPARGPPARD | |
| SCHEMBL5381122 | 0.89 | PPARG (1.00) | PPARAPPARGPPARDLMNAL3MBTL1 | |
| SCHEMBL5381119 | 0.89 | PPARG (1.00) | PPARAPPARGPPARDLMNAL3MBTL1 | |
| SCHEMBL5379700 | 0.88 | PPARG (0.80) | PPARAPPARGPPARDACHEBCHE | |
| SCHEMBL14366450 | 0.88 | PPARG (0.80) | PPARAPPARGPPARDACHEBCHE | |
| SCHEMBL5380299 | 0.87 | PPARG (0.60) | PPARAPPARGPPARD | |
| SCHEMBL5383860 | 0.87 | PPARG (0.95) | PPARAPPARGPPARDLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | PPARG, NCOA4, PPARA | PPARA 3/4885PPARG 1/4885PPARD 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.