Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 8/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.46 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.46 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14366564 | 0.99 | PARP1 (0.50) | PARP1MAPK10RIPK1KDRTLR9 | |
| SCHEMBL14366570 | 0.99 | PARP1 (0.50) | PARP1MAPK10RIPK1KDRTLR9 | |
| SCHEMBL14366566 | 0.99 | PARP1 (0.50) | PARP1MAPK10RIPK1KDRTLR9 | |
| SCHEMBL14366562 | 0.99 | PARP1 (0.50) | PARP1MAPK10RIPK1KDRTLR9 | |
| Hydrochloric Acid SCHEMBL5583141 | 0.99 | PARP1 (0.49) | PARP1MAPK10RIPK1KDRTLR9 | |
| Hydrochloric Acid SCHEMBL5582994 | 0.98 | PARP1 (0.49) | PARP1MAPK10RIPK1KDRTLR9 | |
| Hydrochloric Acid SCHEMBL5582970 | 0.98 | PARP1 (0.49) | PARP1MAPK10RIPK1KDRTLR9 | |
| Hydrochloric Acid SCHEMBL5583262 | 0.98 | PARP1 (0.49) | PARP1MAPK10RIPK1KDRTLR9 | |
| Hydrochloric Acid SCHEMBL5583219 | 0.98 | PARP1 (0.49) | PARP1MAPK10RIPK1KDRTLR9 | |
| SCHEMBL14366595 | 0.98 | PARP1 (0.49) | PARP1MAPK10RIPK1KDRTLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254877-A1 | Indole Derivative and Use for Treatment of Cancer | TAKADA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-11-01 | — | — | US | disclosed |
| US-20070254877-A1 | Indole Derivative and Use for Treatment of Cancer | TAKADA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254877-A1 | Indole Derivative and Use for Treatment of Cancer | IGF1R, KDR, ERBB2 | PARP1 1810/4885MAPK10 1222/4885RIPK1 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.