Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.62 |
| ▸ | PPARA | Q07869 | 11/20 | 0.62 |
| ▸ | PPARD | Q03181 | 7/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383987 | 1.00 | PPARG (0.62) | PPARGPPARAPPARDMRGPRX4NR4A2 | |
| SCHEMBL5385422 | 0.91 | PPARG (0.66) | PPARGPPARAPPARDGPR34 | |
| SCHEMBL27871770 | 0.88 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL5389975 | 0.88 | PPARG (0.72) | PPARGPPARAPPARDGPR34MAOB | |
| SCHEMBL14366608 | 0.87 | PPARG (0.56) | PPARGPPARAPPARDMRGPRX4MAOB | |
| SCHEMBL5389692 | 0.87 | PPARG (0.56) | PPARGPPARAPPARDMRGPRX4MAOB | |
| SCHEMBL12532016 | 0.87 | PPARG (0.63) | PPARGPPARAPPARDSLC1A1 | |
| SCHEMBL5379645 | 0.86 | PPARG (0.72) | PPARGPPARAPPARD | |
| SCHEMBL5390649 | 0.84 | PPARG (0.62) | PPARGPPARAPPARDMRGPRX4MAOB | |
| SCHEMBL14366451 | 0.81 | PPARG (0.81) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | PPARG, NCOA4, PPARA | PPARG 1/4885PPARA 3/4885PPARD 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.