Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.64 |
| ▸ | CNR1 | P21554 | 5/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623378 | 0.78 | CNR2 (1.00) | CNR2CNR1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL11185044 | 0.78 | MAPK1 (0.77) | CNR2CNR1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL5623047 | 0.78 | MAPK1 (0.77) | CNR2CNR1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL5623628 | 0.77 | CNR2 (1.00) | CNR2CNR1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL14367334 | 0.76 | MAPK1 (1.00) | CNR2CNR1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL4204208 | 0.75 | MAPK1 (0.73) | CNR2CNR1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL14367344 | 0.74 | CNR2 (0.78) | CNR2CNR1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL5623866 | 0.73 | CNR2 (0.66) | CNR2CNR1KMT2AGAATSHR | |
| SCHEMBL5623747 | 0.71 | CNR2 (0.67) | CNR2CNR1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL5623351 | 0.71 | MAPT (0.53) | CNR2CNR1MAPK1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297796-B2 | Sulfamoyl benzamide derivatives and methods of their use | ADOLOR CORPORATION (US) | 2007-11-20 | — | — | US | disclosed |