Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 10/20 | 0.68 |
| ▸ | F2 | P00734 | 2/20 | 0.66 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.66 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.66 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.66 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.66 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524345 | 0.82 | PRSS1 (1.00) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL3875680 | 0.78 | PRSS1 (0.84) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL12461511 | 0.77 | PRSS1 (0.82) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| Hydrochloric Acid SCHEMBL1714389 | 0.76 | PRSS1 (0.83) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL14367460 | 0.76 | PRSS1 (0.86) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| Hydrochloric Acid SCHEMBL5623902 | 0.74 | PRSS1 (0.86) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL17515720 | 0.73 | PRSS1 (0.75) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL14367399 | 0.73 | PRSS1 (0.40) | PRSS1F2PRSS2PRSS3ST14 | |
| SCHEMBL14367357 | 0.73 | PRSS1 (0.70) | PRSS1F2ST14 | |
| SCHEMBL14393273 | 0.72 | CYP1B1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |