Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 10/20 | 0.68 |
| ▸ | F2 | P00734 | 1/20 | 0.68 |
| ▸ | PLG | P00747 | 1/20 | 0.68 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.68 |
| ▸ | C1S | P09871 | 1/20 | 0.68 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.68 |
| ▸ | F10 | P00742 | 2/20 | 0.67 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5623120 | 0.99 | PRSS1 (0.69) | PRSS1F2PLGPRSS2C1S | |
| SCHEMBL12461520 | 0.89 | PRSS1 (0.73) | PRSS1F2PLGPRSS2PRSS3 | |
| SCHEMBL14599540 | 0.87 | PRSS1 (0.88) | PRSS1F2PLGPRSS2C1S | |
| SCHEMBL12461759 | 0.87 | PRSS1 (0.71) | PRSS1F2PLGPRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL5623183 | 0.87 | PRSS1 (0.74) | PRSS1F2PLGPRSS2PRSS3 | |
| SCHEMBL12460737 | 0.87 | PRSS1 (0.76) | PRSS1F2PLGPRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL5623287 | 0.86 | PRSS1 (0.72) | PRSS1F2PLGF10TMPRSS2 | |
| SCHEMBL12461903 | 0.86 | PRSS1 (0.69) | PRSS1F2PLGF10TMPRSS2 | |
| Hydrochloric Acid SCHEMBL5623136 | 0.85 | PRSS1 (0.77) | PRSS1F2PLGPRSS2PRSS3 | |
| SCHEMBL14367440 | 0.85 | PRSS1 (0.73) | PRSS1F2PLGF10TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |