SCHEMBL14368409

SCHEMBL14368409

CCNC(=O)N1CCn2c(c(C(N)=O)c(Cl)c2-c2ccccc2)C1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 20/20 0.60
CSNK1D P48730 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13964385 0.88 CSNK1E (0.56) CSNK1E
SCHEMBL4037712 0.87 CSNK1E (0.55) CSNK1ECSNK1D
SCHEMBL4043855 0.86 CSNK1E (0.55) CSNK1E
SCHEMBL13964130 0.85 CSNK1E (0.64) CSNK1ECSNK1D
SCHEMBL13964190 0.85 CSNK1E (0.70) CSNK1ECSNK1D
SCHEMBL14368388 0.85 CSNK1E (0.53) CSNK1ECSNK1D
SCHEMBL13963918 0.82 CSNK1E (0.52) CSNK1ECSNK1D
SCHEMBL14368412 0.82 CSNK1E (0.51) CSNK1E
SCHEMBL14368385 0.82 POLB (0.52) CSNK1ECSNK1D
SCHEMBL13964272 0.82 CSNK1E (0.48) CSNK1E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070238734-A1 JNK INHIBITORS SANOLI-AVENTIS (FR) 2007-10-11 US disclosed
US-20070238734-A1 JNK INHIBITORS SANOLI-AVENTIS (FR) 2007-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238734-A1 JNK INHIBITORS MAP3K7, MAPKAPK2, MAPK7 CSNK1E 136/4885CSNK1D 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.