Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.66 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.56 |
| ▸ | PREP | P48147 | 8/20 | 0.49 |
| ▸ | FAP | Q12884 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666982 | 1.00 | DPP4 (0.66) | DPP4DPP8DPP7PREPFAP | |
| SCHEMBL666983 | 1.00 | DPP4 (0.66) | DPP4DPP8DPP7PREPFAP | |
| SCHEMBL663957 | 0.85 | DPP4 (0.75) | DPP4DPP8DPP7PREPFAP | |
| SCHEMBL7188500 | 0.85 | DPP4 (0.75) | DPP4DPP8DPP7PREPFAP | |
| SCHEMBL663958 | 0.85 | DPP4 (0.75) | DPP4DPP8DPP7PREPFAP | |
| SCHEMBL665383 | 0.83 | DPP4 (0.71) | DPP4DPP8DPP7PREPFAP | |
| SCHEMBL665384 | 0.83 | DPP4 (0.71) | DPP4DPP8DPP7PREPFAP | |
| SCHEMBL665439 | 0.80 | DPP4 (0.64) | DPP4DPP8DPP7PREPFAP | |
| SCHEMBL664749 | 0.80 | DPP4 (1.00) | DPP4DPP8DPP7PREPFAP | |
| SCHEMBL664750 | 0.80 | DPP4 (1.00) | DPP4DPP8DPP7PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441719-B1 | N-SUBSTITUTED PYRROLIDIN DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-03-30 | — | — | EP | disclosed |