Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14372247 | 0.82 | MAPK1 (0.33) | BRD9GSK3AGSK3BMAPK1 | |
| SCHEMBL13006868 | 0.82 | GSK3A (0.36) | BRD9GSK3AGSK3BMAPK1 | |
| SCHEMBL6760743 | 0.80 | BRD9 (0.39) | BRD9MAPK1 | |
| SCHEMBL14372253 | 0.73 | BRD9 (0.35) | BRD9 | |
| SCHEMBL22225023 | 0.68 | MEN1 (0.38) | BRD9GSK3AGSK3B | |
| SCHEMBL17558815 | 0.68 | ADORA2A (0.35) | ADORA3GSK3AGSK3B | |
| SCHEMBL14372204 | 0.67 | MAPK1 (0.33) | BRD9MAPK1 | |
| SCHEMBL14400373 | 0.64 | MAPK1 (0.47) | MAPK1 | |
| SCHEMBL8768659 | 0.64 | KDM4E (0.35) | — | |
| SCHEMBL13006859 | 0.64 | MAPK1 (0.36) | GSK3AGSK3BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |