Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12670054 | 1.00 | CYP2C9 (0.32) | CYP2C9LMNAMAPTCYP2C19L3MBTL1 | |
| SCHEMBL12670048 | 1.00 | CYP2C9 (0.32) | CYP2C9LMNAMAPTCYP2C19L3MBTL1 | |
| SCHEMBL12301675 | 0.98 | POLB (0.30) | — | |
| SCHEMBL14375018 | 0.94 | — | — | |
| SCHEMBL19369950 | 0.89 | — | — | |
| SCHEMBL12670055 | 0.82 | — | — | |
| SCHEMBL4616715 | 0.81 | CYP2C19 (0.39) | CYP2C9LMNAMAPTCYP2C19L3MBTL1 | |
| SCHEMBL12670052 | 0.80 | HTT (0.35) | — | |
| SCHEMBL12670061 | 0.80 | — | — | |
| SCHEMBL12828035 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312211-B2 | Pryanone compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2007-12-25 | — | — | US | disclosed |