Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16479714 | 0.92 | KDM4E (0.46) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL8510100 | 0.87 | KDM4E (0.42) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL15901247 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL14377117 | 0.85 | KDM4E (0.44) | KDM4EMEN1KMT2ARXFP1MAPT | |
| SCHEMBL15908096 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL16476450 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL15908088 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1HPGDGAAGLA | |
| Bromide SCHEMBL15901676 | 0.83 | KDM4E (0.40) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL16476444 | 0.83 | KDM4E (0.40) | KDM4EALDH1A1HPGDGAAGLA | |
| Iodide SCHEMBL29959754 | 0.83 | KDM4E (0.39) | KDM4EALDH1A1HPGDGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012175730-A1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | TriOpto Tec GmbH (DE) | 2012-12-27 | — | — | WO | disclosed |