Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585368 | 0.95 | STAT3 (0.45) | STAT3STAT1CCNB2CDK1CCNB1 | |
| SCHEMBL585041 | 0.87 | STAT3 (0.46) | STAT3STAT1CCNB2CDK1CCNB1 | |
| SCHEMBL14848717 | 0.84 | STAT3 (0.47) | STAT3STAT1MAPTTSHRCYP1A2 | |
| SCHEMBL585685 | 0.84 | STAT3 (0.46) | STAT3STAT1GCGRGPR84PTGS2 | |
| SCHEMBL585880 | 0.83 | STAT3 (0.41) | STAT3STAT1CCNB2CDK1CCNB1 | |
| SCHEMBL17419215 | 0.83 | STAT3 (0.43) | STAT3STAT1GHSRGPR84PTGS2 | |
| SCHEMBL16882035 | 0.82 | STAT3 (0.47) | STAT3STAT1 | |
| SCHEMBL15693593 | 0.82 | STAT3 (0.40) | STAT3STAT1CCNB2CDK1CCNB1 | |
| SCHEMBL10084843 | 0.82 | STAT3 (0.40) | STAT3STAT1CCNB2CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL583840 | 0.82 | STAT3 (0.40) | STAT3STAT1CCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578750-B1 | CATIONIC PORPHYRIN DERIVATIVES AS ANTIBACTERIAL AGENTS | DESTINY PHARMA LTD (GB) | 2007-11-21 | — | — | EP | disclosed |