SCHEMBL14384458

SCHEMBL14384458

CC1(C)CC=C(c2cc(C3(N)CCCCC3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14385422 0.94 CSF1R (0.52) CSF1R
SCHEMBL14383756 0.91 CSF1R (0.52) CSF1R
SCHEMBL14383726 0.91 — —
SCHEMBL14383741 0.90 — —
SCHEMBL14374712 0.90 CSF1R (0.54) CSF1R
SCHEMBL14385435 0.90 CSF1R (0.51) CSF1R
SCHEMBL14385428 0.89 — —
SCHEMBL3972123 0.89 CSF1R (0.53) CSF1R
SCHEMBL14383673 0.88 CSF1R (0.54) CSF1R
SCHEMBL14385447 0.88 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007124322-A1 INHIBITORS OF C-FMS KINASE JANSSEN PHARMACEUTICA N.V. (BE) 2007-11-01 — — WO disclosed
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