Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENTPD2 | Q9Y5L3 | 3/20 | 0.61 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.59 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.53 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.53 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 8/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.45 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14384430 | 0.81 | SLC28A1 (0.61) | ENTPD2SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL13211009 | 0.81 | ENTPD2 (0.55) | ENTPD2ENTPD1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL3023058 | 0.80 | ENTPD2 (0.79) | ENTPD2ENTPD1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL3023054 | 0.80 | ENTPD2 (0.79) | ENTPD2ENTPD1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL13210979 | 0.80 | ENTPD2 (0.90) | ENTPD2ENTPD1P2RY14P2RY2P2RY6 | |
| SCHEMBL3019419 | 0.79 | ENTPD2 (0.62) | ENTPD2ENTPD1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL3019416 | 0.79 | ENTPD2 (0.62) | ENTPD2ENTPD1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL3023061 | 0.79 | ENTPD2 (0.72) | ENTPD2ENTPD1P2RY14P2RY2P2RY6 | |
| SCHEMBL3024200 | 0.79 | ENTPD1 (0.80) | ENTPD2ENTPD1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL3024202 | 0.79 | ENTPD1 (0.80) | ENTPD2ENTPD1SLC28A1SLC28A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135195-A1 | ECTONUCLEOTIDASE INHIBITORS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2007-11-29 | — | — | WO | disclosed |
| EP-1860113-A1 | Ectonucleotidase inhibitors | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2007-11-28 | — | — | EP | disclosed |