SCHEMBL14385010

SCHEMBL14385010

Nc1c[nH]c(C(=O)Nc2ccc(C3(C(=O)O)CCOCC3)cc2C2=CCCCC2)n1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14374624 0.88 CSF1R (0.49) CSF1R
SCHEMBL3974932 0.88 CSF1R (0.54) CSF1R
SCHEMBL14385150 0.88 CSF1R (0.46) CSF1R
SCHEMBL14385012 0.87 — —
SCHEMBL14385170 0.84 CSF1R (0.49) CSF1R
SCHEMBL14374640 0.82 CSF1R (0.48) CSF1R
SCHEMBL14374907 0.82 CSF1R (0.54) CSF1R
SCHEMBL14385095 0.80 — —
SCHEMBL3969836 0.80 CSF1R (0.54) CSF1R
SCHEMBL14374680 0.80 CSF1R (0.49) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007124319-A1 INHIBITORS OF C-FMS KINASE JANSSEN PHARMACEUTICA N.V. (BE) 2007-11-01 — — WO disclosed
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