Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | MVD | P53602 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | EYA2 | O00167 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | BHMT | Q93088 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2000449 | 0.97 | CA12 (0.50) | CA12CA2CA3CA4CA6 | |
| SCHEMBL7796153 | 0.95 | CA12 (0.48) | CA12CA2CA3CA4CA6 | |
| SCHEMBL918386 | 0.89 | TDP1 (0.50) | CA12CA2CA3CA4CA6 | |
| SCHEMBL27018147 | 0.89 | TDP1 (0.58) | CA12CA2CA3CA4CA6 | |
| SCHEMBL14392744 | 0.86 | TDP1 (0.64) | CA12CA2CA3CA4CA6 | |
| SCHEMBL27018199 | 0.85 | MVD (0.43) | MVDTDP1EYA2APPACE | |
| SCHEMBL29222973 | 0.83 | MVD (0.42) | CA12CA2CA3CA4CA6 | |
| SCHEMBL16576609 | 0.82 | TDP1 (0.41) | CA12CA2CA3CA4CA6 | |
| Acetic Acid SCHEMBL7116566 | 0.81 | CA12 (0.65) | CA12CA2CA3CA4CA6 | |
| SCHEMBL25134157 | 0.81 | MVD (0.41) | CA12CA2CA3CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007128873-A1 | A METHOD FOR THE PREPARATION OF MALEIMIDO DERIVATIVES OF BIOMOLECULE LABELING REACTANTS AND CONJUGATES DERIVED THEREOF | WALLAC OY (FI) | 2007-11-15 | — | — | WO | disclosed |