Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 12/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.48 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.46 |
| ▸ | PIK3C2G | O75747 | 2/20 | 0.46 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.46 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4228121 | 1.00 | PIK3CD (0.51) | PIK3CDPIK3CGPI4KBPIK3CAPIK3CB | |
| SCHEMBL4228117 | 1.00 | PIK3CD (0.51) | PIK3CDPIK3CGPI4KBPIK3CAPIK3CB | |
| SCHEMBL14385618 | 0.95 | PIK3CD (0.50) | PIK3CDPIK3CGPI4KBPIK3CAPIK3CB | |
| SCHEMBL14385578 | 0.93 | PIK3CD (0.53) | PIK3CDPIK3CGPI4KBPIK3CAPIK3CB | |
| SCHEMBL14385599 | 0.88 | PIK3CD (0.49) | PIK3CDPIK3CGPI4KBPIK3CAPIK3CB | |
| SCHEMBL14385602 | 0.88 | PIK3CD (0.49) | PIK3CDPIK3CGPI4KBPIK3CAPIK3CB | |
| SCHEMBL14385432 | 0.88 | PIK3CD (0.51) | PIK3CDPIK3CGPI4KBPIK3CAPIK3CB | |
| SCHEMBL3171893 | 0.87 | PIK3CD (0.53) | PIK3CDPIK3CGPI4KBPIK3CAPIK3CB | |
| SCHEMBL4233323 | 0.86 | PIK3CD (0.52) | PIK3CDPIK3CGPI4KBPIK3CAPIK3CB | |
| SCHEMBL4233326 | 0.86 | PIK3CD (0.52) | PIK3CDPIK3CGPI4KBPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007129005-A1 | AMINOACID DERIVATIVES OF THIAZOLES AS INHIBITORS OF PI3 KINASE | CHROMA THERAPEUTICS LTD. (GB) | 2007-11-15 | — | — | WO | disclosed |