Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 8/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.45 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.45 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14385489 | 0.91 | PIK3CD (0.47) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL14385564 | 0.89 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL3174782 | 0.82 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL3175143 | 0.81 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL13525523 | 0.81 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL3168520 | 0.80 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL3176947 | 0.79 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL14385578 | 0.79 | PIK3CD (0.53) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL3176941 | 0.79 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL14385427 | 0.79 | PIK3CD (0.50) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007129005-A1 | AMINOACID DERIVATIVES OF THIAZOLES AS INHIBITORS OF PI3 KINASE | CHROMA THERAPEUTICS LTD. (GB) | 2007-11-15 | — | — | WO | disclosed |