Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.73 |
| ▸ | PIK3CG | P48736 | 17/20 | 0.73 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.73 |
| ▸ | PIK3CB | P42338 | 10/20 | 0.73 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.73 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.73 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.73 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.73 |
| ▸ | PI4KA | P42356 | 1/20 | 0.73 |
| ▸ | PRKDC | P78527 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14385601 | 0.86 | PIK3CD (0.63) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL29373332 | 0.85 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL3175291 | 0.82 | PIK3CD (0.71) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL14384982 | 0.81 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL14851611 | 0.81 | PIK3CG (0.72) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL3167717 | 0.80 | PIK3CD (0.68) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL29180139 | 0.80 | PIK3CD (0.77) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL14851735 | 0.80 | PIK3CD (0.77) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL3170841 | 0.80 | PIK3CD (0.70) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL4222887 | 0.79 | PIK3CD (0.56) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007129005-A1 | AMINOACID DERIVATIVES OF THIAZOLES AS INHIBITORS OF PI3 KINASE | CHROMA THERAPEUTICS LTD. (GB) | 2007-11-15 | — | — | WO | disclosed |