Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26133661 | 0.83 | TSHR (0.63) | TSHR | |
| SCHEMBL6716479 | 0.78 | — | — | |
| SCHEMBL93793 | 0.78 | — | — | |
| SCHEMBL10145998 | 0.78 | TSHR (0.63) | TSHR | |
| SCHEMBL18817846 | 0.78 | TDP1 (0.40) | TSHR | |
| SCHEMBL4551321 | 0.78 | TSHR (0.63) | TSHR | |
| SCHEMBL1960695 | 0.78 | TSHR (0.41) | TSHR | |
| SCHEMBL4742696 | 0.77 | TSHR (0.55) | TSHR | |
| SCHEMBL38573 | 0.77 | — | — | |
| SCHEMBL732555 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007125414-A2 | 9A-SUBSTITUTED AZALIDES FOR THE TRATMENT OF MALARIA | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (GB) | 2007-11-08 | — | — | WO | disclosed |