Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4689679 | 0.90 | P2RY12 (0.56) | P2RY12METAXLGRM1F10 | |
| SCHEMBL14357250 | 0.87 | P2RY12 (0.52) | P2RY12METAXLNOD1GRM1 | |
| SCHEMBL14357216 | 0.86 | P2RY12 (0.54) | P2RY12NOD1GRM1F10 | |
| SCHEMBL14388082 | 0.84 | P2RY12 (0.48) | P2RY12NOD1GRM1 | |
| SCHEMBL14388191 | 0.84 | P2RY12 (0.46) | P2RY12NOD1GRM1F10 | |
| SCHEMBL14388089 | 0.83 | P2RY12 (0.44) | P2RY12NOD1GRM1 | |
| SCHEMBL4686069 | 0.83 | P2RY12 (0.42) | P2RY12METAXLNOD1 | |
| SCHEMBL4681454 | 0.82 | P2RY12 (0.43) | P2RY12METAXLNOD1 | |
| SCHEMBL14387889 | 0.82 | P2RY12 (0.44) | P2RY12NOD1GRM1F10 | |
| SCHEMBL14388093 | 0.82 | P2RY12 (0.46) | P2RY12NOD1GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294635-B2 | Substituted isoquinolinones | PORTOLA PHARMACEUTICALS, INC. (US) | 2007-11-13 | — | — | US | disclosed |