Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4690441 | 0.90 | P2RY12 (0.57) | P2RY12CA12CA1CA2CA9 | |
| SCHEMBL14388167 | 0.89 | P2RY12 (0.41) | P2RY12NOD1FBP1 | |
| SCHEMBL14388082 | 0.88 | P2RY12 (0.48) | P2RY12CA12CA9NOD1 | |
| SCHEMBL14388093 | 0.86 | P2RY12 (0.46) | P2RY12CA12CA1CA2CA9 | |
| SCHEMBL14388193 | 0.86 | P2RY12 (0.43) | P2RY12NOD1FBP1 | |
| SCHEMBL14388192 | 0.85 | P2RY12 (0.42) | P2RY12NOD1FBP1 | |
| SCHEMBL14388169 | 0.85 | P2RY12 (0.43) | P2RY12NOD1TYK2 | |
| SCHEMBL14388191 | 0.84 | P2RY12 (0.46) | P2RY12NOD1 | |
| SCHEMBL14387887 | 0.83 | P2RY12 (0.43) | P2RY12CA12CA1CA2NOD1 | |
| SCHEMBL9922716 | 0.82 | P2RY12 (0.48) | P2RY12CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835444-B2 | Cyclohexyl amide derivatives as CRF receptor antagonists | NOVARTIS AG (CH) | 2014-09-16 | — | — | US | disclosed |
| US-7294635-B2 | Substituted isoquinolinones | PORTOLA PHARMACEUTICALS, INC. (US) | 2007-11-13 | — | — | US | disclosed |