Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 5/20 | 0.51 |
| ▸ | TYMP | P19971 | 9/20 | 0.42 |
| ▸ | MPG | P29372 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14388457 | 0.84 | PNP (0.51) | PNPTYMPMPGGBA1 | |
| SCHEMBL6572738 | 0.75 | TYMP (0.47) | TYMP | |
| SCHEMBL14388454 | 0.73 | PNP (0.60) | PNPMPGGBA1 | |
| SCHEMBL1682985 | 0.71 | TYMP (0.63) | TYMP | |
| SCHEMBL1682926 | 0.71 | TYMP (0.59) | TYMP | |
| SCHEMBL20599962 | 0.67 | TYMP (0.59) | TYMP | |
| SCHEMBL6570534 | 0.66 | TYMP (0.41) | TYMP | |
| SCHEMBL4528469 | 0.64 | GBA1 (0.82) | MPGGBA1 | |
| SCHEMBL500739 | 0.64 | GBA1 (0.82) | MPGGBA1 | |
| SCHEMBL500738 | 0.64 | GBA1 (0.82) | MPGGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275988-A1 | Transition state structure and inhibitors of thymidine phosphorylases | INDUSTRIAL RESEARCH LIMITED (NZ) | 2007-11-29 | — | — | US | disclosed |