⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1440 | 1.00 | — | — | |
| SCHEMBL1441 | 1.00 | — | — | |
| SCHEMBL7672001 | 0.82 | HCAR2 (0.50) | — | |
| SCHEMBL27203936 | 0.81 | — | — | |
| SCHEMBL4667392 | 0.80 | — | — | |
| SCHEMBL3867193 | 0.79 | HCAR2 (0.43) | — | |
| SCHEMBL3867194 | 0.79 | HCAR2 (0.43) | — | |
| SCHEMBL1932544 | 0.78 | — | — | |
| SCHEMBL7660667 | 0.78 | — | — | |
| SCHEMBL11274494 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439096-B1 | Improvements in or relating to beta lactam production | BIOCHEMIE GMBH (AT) | 2003-12-17 | — | — | EP | claimed |
| EP-0195947-B1 | Beta-lactam antibiotics, process for their preparation and their use as and in medicaments | BAYER AG (DE) | 1996-04-24 | — | — | EP | claimed |
| EP-0292806-B1 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1994-11-02 | — | — | EP | claimed |
| US-5276024-A | 3-substituted cephalosporins, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | claimed |
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | claimed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | claimed |
| US-4652679-A | Aziridine and phenethanolamine derivatives having antiobesity and anti-hyperglycaemic acitivity | HOFFMANN-LA ROCHE INC. (US) | 1987-03-24 | — | — | US | claimed |
| EP-0094595-B1 | AZIRIDINE AND PHENYLETHANOL AMINE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-01-14 | — | — | EP | claimed |
| EP-0195947-A2 | Beta-lactam antibiotics, process for their preparation and their use as and in medicaments | BAYER AG (DE) | 1986-10-01 | — | — | EP | claimed |
| EP-0186706-A1 | PROCESS FOR PREPARING CEPHALOSPORIN DERIVATIVES | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1986-07-09 | — | — | EP | claimed |
| EP-2464623-B1 | THE RING OPENING OF LACTONES AND LACTAMS | NOVARTIS AG (CH) | 2020-11-04 | — | — | EP | disclosed |
| US-8779198-B2 | Ring opening of lactones and lactams | NOVARTIS AG (CH) | 2014-07-15 | — | — | US | disclosed |
| US-8507673-B2 | Process for preparing 5,7 diaminopyrazolo [1,5-A] pyrimidine compounds | EMORY UNIVERSITY (US) | 2013-08-13 | — | — | US | disclosed |
| US-20120165555-A1 | RING OPENING OF LACTONES AND LACTAMS | NOVARTIS AG (CH) | 2012-06-28 | — | — | US | disclosed |
| US-20120041198-A1 | Process for Preparing 5,7 Diaminopyrazolo [1,5-a] Pyrimidine Compounds | EMORY UNIVERSITY | 2012-02-16 | — | — | US | disclosed |
| US-4013648-A | BETA-LACTAM ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-4012383-A | BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
| US-4011216-A | Δ2,3-0-2-Isocephem-4-carboxylic acid and derivatives thereof as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1977-03-08 | — | — | US | disclosed |
| US-3989685-A | FROM PENICILLIN-1-OXIDE | SHINOGI & CO., LTD. (JA) | 1976-11-02 | — | — | US | disclosed |
| US-3985740-A | THERAPEUTIC AND ANTIBACTERIAL AGENTS | BRISTOL-MYERS COMPANY (US) | 1976-10-12 | — | — | US | disclosed |