Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 11/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13696573 | 1.00 | HRH4 (0.41) | HRH4HRH3CXCR4PRKD1PRKD2 | |
| SCHEMBL2011647 | 0.88 | HRH4 (0.40) | HRH4HRH3CXCR4PRKD1PRKD2 | |
| SCHEMBL15623173 | 0.88 | HRH4 (0.40) | HRH4HRH3CXCR4PRKD1PRKD2 | |
| SCHEMBL4105443 | 0.81 | HRH4 (0.41) | HRH4HRH3CXCR4 | |
| SCHEMBL2011401 | 0.81 | HRH4 (0.41) | HRH4HRH3CXCR4 | |
| SCHEMBL13696576 | 0.81 | HRH4 (0.41) | HRH4HRH3CXCR4 | |
| SCHEMBL13696535 | 0.81 | HRH4 (0.41) | HRH4HRH3CXCR4 | |
| SCHEMBL2014328 | 0.81 | HRH4 (0.41) | HRH4HRH3CXCR4 | |
| Hydrochloric Acid SCHEMBL4120882 | 0.80 | HRH4 (0.41) | HRH4HRH3CXCR4 | |
| Hydrochloric Acid SCHEMBL4116285 | 0.80 | HRH4 (0.41) | HRH4HRH3CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852432-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-11-07 | — | — | EP | disclosed |