Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 8/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4108663 | 0.89 | CXCR4 (0.43) | CCR4DGAT2MAPK10MAPK8MAPK9 | |
| SCHEMBL2013385 | 0.86 | CCR4 (0.39) | CCR4DGAT2MAPK10MAPK8MAPK9 | |
| SCHEMBL13696567 | 0.86 | CCR4 (0.39) | CCR4DGAT2MAPK10MAPK8MAPK9 | |
| SCHEMBL2011571 | 0.83 | CXCR4 (0.42) | CCR4DGAT2MAPK10MAPK8MAPK9 | |
| SCHEMBL2007163 | 0.83 | CXCR4 (0.42) | CCR4DGAT2MAPK10MAPK8MAPK9 | |
| SCHEMBL4110231 | 0.83 | CXCR4 (0.42) | CCR4DGAT2MAPK10MAPK8MAPK9 | |
| SCHEMBL4110035 | 0.83 | CXCR4 (0.42) | CCR4DGAT2MAPK10MAPK8MAPK9 | |
| SCHEMBL4116420 | 0.82 | CXCR4 (0.43) | CXCR4HRH4 | |
| SCHEMBL4116178 | 0.82 | CCR4 (0.41) | CCR4DGAT2MAPK10MAPK8MAPK9 | |
| SCHEMBL13696571 | 0.79 | HRH4 (0.40) | CCR4CXCR4HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852432-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-11-07 | — | — | EP | disclosed |