Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007560 | 1.00 | CXCR4 (0.47) | CXCR4MAPK8HRH4MAPK9MAPK10 | |
| SCHEMBL4105351 | 1.00 | CXCR4 (0.47) | CXCR4MAPK8HRH4MAPK9MAPK10 | |
| SCHEMBL2007558 | 1.00 | CXCR4 (0.47) | CXCR4MAPK8HRH4MAPK9MAPK10 | |
| SCHEMBL4105357 | 1.00 | CXCR4 (0.47) | CXCR4MAPK8HRH4MAPK9MAPK10 | |
| SCHEMBL230553 | 0.92 | CXCR4 (0.51) | CXCR4MAPK8HRH4 | |
| SCHEMBL229157 | 0.92 | CXCR4 (0.51) | CXCR4MAPK8HRH4 | |
| SCHEMBL4110214 | 0.90 | CXCR4 (0.42) | CXCR4MAPK8HRH4MAPK9MAPK10 | |
| SCHEMBL4110212 | 0.90 | CXCR4 (0.42) | CXCR4MAPK8HRH4MAPK9MAPK10 | |
| SCHEMBL4110591 | 0.90 | CXCR4 (0.50) | CXCR4MAPK8HRH4MAPK9 | |
| SCHEMBL230622 | 0.89 | CXCR4 (0.49) | CXCR4MAPK8HRH4MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852432-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-11-07 | — | — | EP | disclosed |