Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 20/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14394458 | 1.00 | CCR3 (0.50) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL14369006 | 0.92 | CCR3 (0.48) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL14392359 | 0.92 | CCR3 (0.48) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL4431718 | 0.92 | CCR3 (0.48) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL14369133 | 0.92 | CCR3 (0.48) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL5659731 | 0.91 | CCR3 (0.47) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL14368665 | 0.90 | CCR3 (0.51) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL14394453 | 0.84 | CCR3 (0.45) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL4553275 | 0.80 | CCR3 (0.46) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL4435281 | 0.80 | CCR3 (0.46) | CCR3CYP2D6DRD2SLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007126362-A1 | COMPOUNDS THAT ARE AGONISTS OF MUSCARINIC RECEPTORS AND THAT MAY BE EFFECTIVE IN TREATING PAIN, ALZHEIMER'S DISEASE AND/OR SCHIZOPHRENIA | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | WO | disclosed |