Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.68 |
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404677 | 0.90 | CD274 (0.71) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL23840700 | 0.87 | CD274 (0.71) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL7451212 | 0.85 | CD274 (0.73) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL20671965 | 0.85 | CD274 (0.68) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL15947384 | 0.85 | CD274 (0.68) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL8404675 | 0.84 | CD274 (0.71) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL28212521 | 0.84 | CD274 (0.71) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL2251460 | 0.84 | CD274 (0.76) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL280240 | 0.84 | MEN1 (0.76) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL19634426 | 0.84 | CD274 (0.67) | CD274ALDH1A1HTR1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300936-B2 | α-(N-sulfonamido)acetamide derivatives as β-amyloid inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-11-27 | — | — | US | disclosed |