Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19793111 | 0.78 | GCK (0.55) | GCKKCNH2 | |
| SCHEMBL19792905 | 0.78 | GCK (0.55) | GCKKCNH2 | |
| SCHEMBL19793113 | 0.77 | GCK (0.54) | GCKKCNH2 | |
| SCHEMBL19793123 | 0.77 | GCK (0.54) | GCKKCNH2 | |
| SCHEMBL3609595 | 0.74 | GCK (0.56) | GCKKCNH2 | |
| SCHEMBL13255207 | 0.74 | GCK (0.56) | GCKKCNH2 | |
| SCHEMBL669917 | 0.73 | GCK (0.70) | GCKKCNH2 | |
| SCHEMBL13255202 | 0.73 | GCK (0.70) | GCKKCNH2 | |
| SCHEMBL21193748 | 0.69 | GCK (0.55) | GCKKCNH2 | |
| SCHEMBL19792898 | 0.69 | GCK (0.55) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473047-A1 | AMINOTETRAHYDROPYRANS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | Merck Sharp & Dohme Corp. (US) | 2012-07-11 | — | — | EP | disclosed |
| WO-2011028455-A1 | AMINOTETRAHYDROPYRANS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK SHARP & DOHME CORP. (US) | 2011-03-10 | — | — | WO | disclosed |