Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.77 |
| ▸ | MC5R | P33032 | 2/20 | 0.77 |
| ▸ | MC3R | P41968 | 2/20 | 0.77 |
| ▸ | MC1R | Q01726 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13123993 | 0.91 | MC4R (0.84) | MC4RMC5RMC3RMC1R | |
| SCHEMBL5244324 | 0.91 | MC4R (0.84) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13123971 | 0.91 | MC4R (0.86) | MC4RMC5RMC3RMC1R | |
| Hydrochloric Acid SCHEMBL3803207 | 0.90 | MC4R (0.83) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13123973 | 0.89 | MC4R (0.85) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13123978 | 0.88 | MC4R (0.98) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13124020 | 0.87 | MC4R (0.88) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13123987 | 0.87 | MC4R (1.00) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13123991 | 0.86 | MC4R (0.86) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13123891 | 0.85 | MC4R (0.84) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599167-B1 | BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES HAVING AFFINITY FOR THE MELANOCORTIN RECEPTORS AND USE THEREOF AS A MEDICAMENT | SOD CONSEILS RECH APPLIC (FR) | 2007-10-03 | — | — | EP | disclosed |