Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
| ▸ | NQO2 | P16083 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439492 | 1.00 | MEN1 (0.59) | MEN1KMT2AALDH1A1PTGS1HTT | |
| SCHEMBL27838696 | 0.89 | MEN1 (0.64) | MEN1KMT2AALDH1A1PTGS1POLB | |
| SCHEMBL1439917 | 0.87 | PTGS1 (0.58) | MEN1KMT2AALDH1A1PTGS1NQO2 | |
| SCHEMBL1439916 | 0.87 | PTGS1 (0.58) | MEN1KMT2AALDH1A1PTGS1HTT | |
| SCHEMBL3793636 | 0.87 | MEN1 (0.61) | MEN1KMT2AALDH1A1PTGS1POLB | |
| SCHEMBL3793631 | 0.87 | MEN1 (0.61) | MEN1KMT2AALDH1A1PTGS1POLB | |
| SCHEMBL3802163 | 0.87 | MEN1 (0.61) | MEN1KMT2AALDH1A1PTGS1POLB | |
| SCHEMBL4659518 | 0.85 | MEN1 (0.59) | MEN1KMT2AALDH1A1PTGS1POLB | |
| SCHEMBL4659524 | 0.85 | MEN1 (0.59) | MEN1KMT2AALDH1A1PTGS1POLB | |
| SCHEMBL3044137 | 0.83 | MEN1 (0.74) | MEN1KMT2AALDH1A1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263044-B2 | Stilbene like compounds as novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2012-09-11 | — | — | US | disclosed |
| US-8263044-B2 | Stilbene like compounds as novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2012-09-11 | — | — | US | disclosed |
| US-8263044-B2 | Stilbene like compounds as novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2012-09-11 | — | — | US | disclosed |
| WO-2007054776-A9 | STILBENE LIKE COMPOUNDS AS NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-03-03 | — | — | WO | disclosed |
| WO-2007054776-A9 | STILBENE LIKE COMPOUNDS AS NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-03-03 | — | — | WO | disclosed |
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-05-28 | — | — | US | disclosed |
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-05-28 | — | — | US | disclosed |
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-05-28 | — | — | US | disclosed |
| WO-2007054776-A2 | STILBENE LIKE COMPOUNDS AS NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007054776-A2 | STILBENE LIKE COMPOUNDS AS NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | HDAC1, HDAC5, HDAC11 | MEN1 3883/4885KMT2A 265/4885ALDH1A1 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.