Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.55 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | MC5R | P33032 | 1/20 | 0.43 |
| ▸ | MC3R | P41968 | 1/20 | 0.43 |
| ▸ | MC1R | Q01726 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13124680 | 0.87 | MC4R (0.62) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13124632 | 0.86 | MC4R (0.63) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13124630 | 0.77 | MC4R (0.78) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13124769 | 0.74 | MC4R (0.64) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13123858 | 0.74 | MC4R (0.79) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13124455 | 0.74 | MC4R (0.65) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13123856 | 0.73 | MC4R (0.78) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13124994 | 0.72 | MC4R (0.82) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13124684 | 0.72 | MC4R (0.81) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13124676 | 0.72 | MC4R (0.70) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599167-B1 | BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES HAVING AFFINITY FOR THE MELANOCORTIN RECEPTORS AND USE THEREOF AS A MEDICAMENT | SOD CONSEILS RECH APPLIC (FR) | 2007-10-03 | — | — | EP | disclosed |