Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 13/20 | 0.62 |
| ▸ | CDK9 | P50750 | 7/20 | 0.51 |
| ▸ | CCNK | O75909 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439347 | 1.00 | CCNT1 (0.62) | CCNT1CDK9CCNKPOLB | |
| SCHEMBL10285625 | 1.00 | CCNT1 (0.62) | CCNT1CDK9CCNKPOLB | |
| SCHEMBL12818257 | 0.94 | CCNT1 (0.61) | CCNT1CDK9CCNK | |
| SCHEMBL1439961 | 0.94 | CCNT1 (0.62) | CCNT1CDK9CCNK | |
| SCHEMBL1439893 | 0.94 | CCNT1 (0.62) | CCNT1CDK9CCNK | |
| SCHEMBL10285750 | 0.93 | CCNT1 (0.61) | CCNT1CDK9CCNK | |
| SCHEMBL1439529 | 0.92 | CCNT1 (0.60) | CCNT1CDK9CCNK | |
| SCHEMBL12819649 | 0.92 | CCNT1 (0.52) | CCNT1CDK9POLB | |
| SCHEMBL1439813 | 0.92 | CCNT1 (0.60) | CCNT1CDK9CCNK | |
| SCHEMBL1946729 | 0.91 | CCNT1 (0.56) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011026904-A1 | PYRAZINYLPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2011-03-10 | — | — | WO | claimed |
| WO-2011026904-A1 | PYRAZINYLPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2011-03-10 | — | — | WO | disclosed |