Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 15/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.38 |
| ▸ | FLT3 | P36888 | 4/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | PI4KA | P42356 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2676596 | 0.93 | USP30 (0.40) | CSF1RUSP30PDGFRAFLT3PDGFRB | |
| SCHEMBL2676592 | 0.93 | USP30 (0.40) | CSF1RUSP30PDGFRAFLT3PDGFRB | |
| SCHEMBL2676644 | 0.92 | CSF1R (0.44) | CSF1RUSP30PDGFRAFLT3PDGFRB | |
| SCHEMBL2676648 | 0.92 | CSF1R (0.44) | CSF1RUSP30PDGFRAFLT3PDGFRB | |
| SCHEMBL4373929 | 0.91 | CSF1R (0.38) | CSF1RUSP30PDGFRAFLT3PDGFRB | |
| SCHEMBL2677406 | 0.91 | CSF1R (0.38) | CSF1RUSP30PDGFRAFLT3PDGFRB | |
| SCHEMBL2675565 | 0.91 | CSF1R (0.39) | CSF1RUSP30PDGFRAFLT3PDGFRB | |
| SCHEMBL2675566 | 0.91 | CSF1R (0.39) | CSF1RUSP30PDGFRAFLT3PDGFRB | |
| SCHEMBL2675941 | 0.90 | USP30 (0.38) | CSF1RUSP30PDGFRAFLT3PDGFRB | |
| SCHEMBL2675944 | 0.90 | USP30 (0.38) | CSF1RUSP30PDGFRAFLT3PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121484-A2 | 6-O-SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE COMPOUNDS AND METHODS OF INHIBITING CSF-1R SIGNALING | NOVARTIS AG (CH) | 2007-10-25 | — | — | WO | disclosed |