Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 19/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 12/20 | 0.59 |
| ▸ | KIT | P10721 | 11/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 11/20 | 0.59 |
| ▸ | FLT3 | P36888 | 11/20 | 0.59 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2676808 | 0.90 | CSF1R (0.61) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| SCHEMBL2677716 | 0.90 | CSF1R (0.59) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| SCHEMBL2676383 | 0.88 | CSF1R (0.62) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| SCHEMBL2677174 | 0.87 | CSF1R (0.57) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| SCHEMBL2677710 | 0.87 | CSF1R (0.57) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| SCHEMBL2677629 | 0.87 | CSF1R (0.60) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| SCHEMBL2676696 | 0.86 | CSF1R (0.61) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| SCHEMBL2677747 | 0.85 | CSF1R (0.62) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| SCHEMBL2677889 | 0.85 | CSF1R (0.60) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| SCHEMBL2676489 | 0.83 | CSF1R (0.57) | CSF1RPDGFRBKITPDGFRAFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121484-A2 | 6-O-SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE COMPOUNDS AND METHODS OF INHIBITING CSF-1R SIGNALING | NOVARTIS AG (CH) | 2007-10-25 | — | — | WO | disclosed |