Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.81 |
| ▸ | ADORA2B | P29275 | 10/20 | 0.81 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115629 | 0.90 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL4153023 | 0.90 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL4152034 | 0.90 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL4151696 | 0.89 | ADORA2A (0.84) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL8102444 | 0.89 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL8102432 | 0.89 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL4152512 | 0.87 | ADORA2A (0.84) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL4152507 | 0.87 | ADORA2A (0.84) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL4157043 | 0.87 | ADORA2A (0.84) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL4156738 | 0.85 | ADORA2A (0.84) | ADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113538-A1 | SUBSTITUTED ADENINES AND THE USES THEREOF | ASTRAZENECA AB (SE) | 2007-10-11 | — | — | WO | disclosed |