SCHEMBL14397173

SCHEMBL14397173

CCNC/C=C\CNC/C=C\CN

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 5/20 0.48
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8925201 0.97
SCHEMBL8925197 0.97
SCHEMBL14350983 0.97
SCHEMBL12951512 0.86 KDM1A (0.60) KDM1ATP53
SCHEMBL12082977 0.86 KDM1A (0.60) KDM1ATP53
SCHEMBL562701 0.83 KDM1A (0.63) KDM1ATP53
SCHEMBL562702 0.83 KDM1A (0.63) KDM1ATP53
SCHEMBL15884022 0.81 KDM1A (0.75) KDM1A
SCHEMBL4031564 0.77
SCHEMBL14468594 0.76 KDM1A (0.50) KDM1ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007111993-A2 POLYAMINE ANALOGS AS THERAPEUTIC AGENTS FOR SKIN DISEASES CELLGATE, INC. (US) 2007-10-04 WO disclosed