SCHEMBL14397200

SCHEMBL14397200

C=C(F)[C@@H](CCOCP(=O)(O)O)n1cnc2c(N)ncnc21

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 2/20 0.58
SLC22A6 Q4U2R8 1/20 0.58
CYP3A4 P08684 1/20 0.47
AHCY P23526 4/20 0.44
ENPP1 P22413 3/20 0.44
ENPP3 O14638 1/20 0.42
ADORA2A P29274 2/20 0.41
ADORA2B P29275 2/20 0.41
ADORA1 P30542 2/20 0.41
PI4KA P42356 1/20 0.41
PI4K2B Q8TCG2 1/20 0.41
PI4K2A Q9BTU6 1/20 0.41
PI4KB Q9UBF8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904118 0.83 FGFR1 (0.60) FGFR1SLC22A6CYP3A4AHCYENPP1
SCHEMBL6905183 0.83 FGFR1 (0.63) FGFR1SLC22A6CYP3A4AHCYENPP1
SCHEMBL6905174 0.82 FGFR1 (0.61) FGFR1SLC22A6CYP3A4AHCYENPP1
SCHEMBL6316076 0.82 FGFR1 (0.61) FGFR1SLC22A6CYP3A4AHCYENPP1
SCHEMBL6904277 0.82 FGFR1 (0.61) FGFR1SLC22A6CYP3A4AHCYENPP1
SCHEMBL13714845 0.80 FGFR1 (0.54) FGFR1SLC22A6CYP3A4AHCYENPP1
SCHEMBL6897641 0.80 FGFR1 (0.59) FGFR1SLC22A6CYP3A4ENPP1ENPP3
SCHEMBL3852148 0.80 FGFR1 (0.54) FGFR1SLC22A6CYP3A4AHCYENPP1
SCHEMBL6690541 0.78 FGFR1 (0.56) FGFR1SLC22A6CYP3A4AHCYENPP1
SCHEMBL6905447 0.77 SLC22A6 (0.55) FGFR1SLC22A6CYP3A4AHCYENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007112028-A2 2'-FLUORONUCLEOSIDE PHOSPHONATES AS ANTIVIRAL AGENTS RFS PHARMA, LLC. (US) 2007-10-04 WO disclosed