Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.61 |
| ▸ | PI4KA | P42356 | 1/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.52 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | AMD1 | P17707 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3876664 | 0.92 | ADORA2A (0.71) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL4236084 | 0.92 | ADORA2A (0.71) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL4145413 | 0.92 | ADORA2A (0.61) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL3889149 | 0.92 | ADORA2A (0.61) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL13855572 | 0.92 | ADORA2A (0.61) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL4153617 | 0.90 | ADORA2A (0.59) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL4148702 | 0.88 | ADORA2A (0.57) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL4156312 | 0.87 | ADORA2A (0.56) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL4157828 | 0.87 | ADORA2A (0.60) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL4164271 | 0.87 | ADORA2A (0.56) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113538-A1 | SUBSTITUTED ADENINES AND THE USES THEREOF | ASTRAZENECA AB (SE) | 2007-10-11 | — | — | WO | disclosed |