Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.64 |
| ▸ | PTGES | O14684 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | TOP2A | P11388 | 1/20 | 0.59 |
| ▸ | NT5E | P21589 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.59 |
| ▸ | CETP | P11597 | 1/20 | 0.57 |
| ▸ | PRKCG | P05129 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13855629 | 0.93 | CA9 (0.71) | CA9CA1CA2SLC10A1PTGES | |
| SCHEMBL208561 | 0.90 | CA9 (0.68) | CA9CA1CA2SLC10A1PTGES | |
| SCHEMBL2733995 | 0.90 | CA9 (0.68) | CA9CA1CA2SLC10A1PTGES | |
| SCHEMBL2734063 | 0.90 | CA9 (0.68) | CA9CA1CA2SLC10A1PTGES | |
| SCHEMBL18711154 | 0.88 | CA9 (0.64) | CA9CA1CA2SLC10A1PTGES | |
| SCHEMBL14399281 | 0.88 | CA9 (0.66) | CA9CA1CA2SLC10A1PTGES | |
| SCHEMBL14374404 | 0.87 | CA9 (0.68) | CA9CA1CA2SLC10A1PTGES | |
| SCHEMBL14397738 | 0.87 | CA9 (0.68) | CA9CA1CA2SLC10A1PTGES | |
| SCHEMBL14374252 | 0.87 | CA9 (0.68) | CA9CA1CA2SLC10A1PTGES | |
| SCHEMBL12325848 | 0.87 | NT5E (0.77) | CA9CA1CA2SLC10A1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007112043-A2 | SYNTHETIC PENTACYCLIC TRITERPENOIDS AND DERIVATIVES OF BETULINIC ACID AND BETULIN | ADVANCED LIFE SCIENCES INC. (US) | 2007-10-04 | — | — | WO | disclosed |