Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.42 |
| ▸ | ACACA | Q13085 | 8/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14372084 | 0.92 | ACACB (0.40) | ACACBACACADPP4GRM1 | |
| SCHEMBL14400413 | 0.89 | ACACB (0.39) | ACACBACACAGRM1SLC6A4SLC6A3 | |
| SCHEMBL14400357 | 0.89 | ACACB (0.39) | ACACBACACAGRM1 | |
| SCHEMBL14372094 | 0.88 | ACACB (0.38) | ACACBACACAGRM1 | |
| SCHEMBL14372086 | 0.88 | ACACB (0.39) | ACACBACACADPP4 | |
| SCHEMBL14372085 | 0.86 | ACACB (0.39) | ACACBACACAGRM1 | |
| SCHEMBL14129278 | 0.84 | ACACB (0.39) | ACACBACACA | |
| SCHEMBL13698887 | 0.84 | ACACB (0.40) | ACACBACACAGRM1 | |
| SCHEMBL14372083 | 0.84 | ACACB (0.52) | ACACBACACADPP4GRM1SLC6A4 | |
| SCHEMBL14372081 | 0.84 | ACACB (0.52) | ACACBACACADPP4GRM1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244007-A1 | Cis-Alkoxyspiro-Substituted Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244007-A1 | Cis-Alkoxyspiro-Substituted Tetramic Acid Derivatives | AGXT, PAOX, DDT | ACACB 823/4885ACACA 516/4885DPP4 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.